Glycerol phenylbutyrate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

苯丁酸甘油酯 (GPB) 是新一代氨清除剂化合物，也是 sigma-2 (σ2) 受体配体 (pKi: 8.02)。苯丁酸甘油酯可能对慢性肝性脑病或其他遗传性代谢性疾病等其他疾病具有治疗潜力。 。苯丁酸甘油酯还具有治疗高氨血症的潜力。

Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).Glycerol phenylbutyrate may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders. Glycerol phenylbutyrate also has the potential for the treatment of hyperammonemia. (In Vivo):Glycerol phenylbutyrate (GPB) has the potential for the treatment of hyperammonemia. Glycerol phenylbutyrate (GPB) may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders.

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Glycerol phenylbutyrate (GPB) has the potential for the treatment of hyperammonemia. Glycerol phenylbutyrate (GPB) may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders.

HPN-100

Autophagy

Sigma receptor

σ2

Urinary system

Urea Cycle Disorders

611168-24-2

530.65

C33H38O6

>98% (HPLC)

DMSO:150 mg/mL (282.67 mM)

O=C(CCCC1=CC=CC=C1)OC(COC(CCCC2=CC=CC=C2)=O)COC(CCCC3=CC=CC=C3)=O

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(-20℃)

With Ice Pack

≥ 2 years